In-utero exposures associated with increased risk of thyroid cancer
Maternal health, in-utero, and perinatal exposures and risk of thyroid cancer in offspring.
A recent study by prof. Tone Bjorge, University of Bergen, and her team shows that thyroid cancer is related to in-utero exposures.Maternal hypothyroidism, hyperthyroidism, goiter, and benign thyroid neoplasms related to higher risk
The teamconducted a nested case-control study using nationwide registry data from four Nordic countries (Denmark, Finland, Norway, and Sweden). The study included 2,437 thyroid cancer cases and 24,362 matched controls aged 0-48 years during 1967-2015.
"Maternal benign thyroid conditions such as hypothyroidism, hyperthyroidism, goiter, and benign thyroid neoplasms were strongly associated with thyroid cancer risk in offspring. Also, high birth weight, congenital hypothyroidism, maternal history of diabetes, and maternal postpartum haemorrhage were associated with increased risk," says Bjorge
Motivation for further research