Can Cystitis Glandularis Become Cancerous without Treatment?

Date:2024-09-26 click:0
Cystitis glandularis, a benign but potentially precancerous bladder condition, requires prompt attention and treatment. Left untreated, this condition may progress to adenocarcinoma, a more serious form of cancer. Understanding the risks and symptoms of cystitis glandularis is crucial for early detection and effective management.
 


Cystitis glandularis is a metaplastic condition affecting the bladder's transitional epithelium. This transformation, where normal bladder lining cells change into glandular epithelium, can occur due to various factors. Patients often experience urinary symptoms such as:

Frequent urination
Urgency to urinate
Pain or discomfort during urination
Dysuria (painful urination)
Hematuria (blood in urine, visible or microscopic)
 
In severe cases, particularly when hydronephrosis (swelling of the kidney due to urine buildup) occurs, patients may also experience back pain and lumbar enlargement.

Diagnosis of Cystitis Glandularis

Accurate diagnosis of cystitis glandularis typically involves:

1. Cystoscopy: A procedure allowing direct visualization of the bladder lining
2. Biopsy: Tissue sampling for microscopic examination
3. Imaging studies: Such as color Doppler ultrasound or CT scans of the bladder

These diagnostic methods help differentiate cystitis glandularis from other bladder conditions and assess the extent of the lesions. Early and accurate diagnosis is crucial for proper management and prevention of potential cancerous transformation.
 
Cancer Risk and Progression of Cystitis Glandularis

Current research shows that cystitis glandularis is a benign lesion, but it has the possibility of malignant transformation and is a precancerous lesion. If it is left untreated, it may develop into adenocarcinoma. It is recommended that the patient go to a regular hospital for a comprehensive examination and perform a color Doppler ultrasound or CT examination of the bladder to clarify further.
 
The clinical manifestations of cystitis glandularis are closely related to the lesion site. The main indication of the lesion in the bladder triangle is bladder irritation. If the lesion occurs in the bladder neck, it is mainly manifested as poor urination and difficulty urinating.
 
Generally, if it presents with severe symptoms such as frequent urination, urgency, and dysuria, nocturia often occurs. If some people have frequent urination, the frequency of urination at night will increase significantly. That is, nocturia will also be apparent.
 
Nocturia occurs in patients with cystitis glandularis. The increased frequency of urination at night has an impact on the overall condition of the body. Frequent urination at night can lead to poor sleep and an imbalance in the body's endocrine system, which affects the patient's work and study.

Treatment Options for Cystitis Glandularis
   
If the disease is not actively treated, it will bring inconvenience to life and work, and it may turn into bladder cancer, so it is recommended that patients with cystitis glandularis take active treatment. Through active treatment, people can relieve the symptoms, reduce the possibility of cystitis glandularis becoming bladder cancer and prevent further aggravation.
 
Aggressive surgery is often required for patients with severe symptoms. Surgery to remove the lesion can prevent cancerous changes in cystitis glandularis. Because cystitis glandularis has a relatively high recurrence rate, patients generally need regular intravesical instillation of drugs to reduce the recurrence rate after surgery. After surgery, patients should also have a periodic review of cystoscopy to detect recurrence and timely treatment.
 
To treat cystitis glandularis, patients can use traditional Chinese medicine Diuretic and Anti-inflammatory Pill. The herbs in this pill, such as plantain seed, Dianthus Superbus, and Polygonum aviculare can relieve stranguria, effectively improve the symptoms of frequent urination and relieve urethral discomfort.
 
In daily life, patients need to take the following nursing measures:
 
1. The patient needs to drink water, urinate regularly, and cannot hold back urine. It is recommended that the patient eat a light diet, not pepper, onion, and garlic cloves, and eat more vegetables and fruits rich in vitamins, such as celery and kiwi.
 
2. Patients can perform local hyperthermia and local acupuncture to promote blood circulation. They also should change their underwear daily and pay attention to perineal hygiene.
 
3. Patients need proper physical exercise to enhance the body's immunity and avoid heavy physical labor. Patients also need to do regular urinalysis and urinary system ultrasound.
 
 
Recommended Readings:
 
Can Cystitis Glandularis be Radically Cured?
Success Case of Cystitis Glandularis with Diuretic and Anti-inflammatory Pill
How to prevent the recurrence of cystitis glandularis after surgery?