Drug Treatment of Chronic Bacterial Prostatitis

Date:2020-04-23 click:0

Chronic bacterial prostatitis is a chronic disease caused by a bacterial infection. Although some patients undergo systematic and regular antibacterial treatment, they will still have delays or relapse. Some researchers think that in clinical, some patients choose sensitive drugs in the treatment. In addition to the above reasons, some staphylococci formed biofilm in the prostatic duct, which hindered the killing effect of antibiotics on bacteria.
Pharmacokinetic studies and clinical experience have shown that only a few antibiotics can achieve effective therapeutic concentration in prostatic secretion under the condition of nonacute prostatitis.
TMP can penetrate into prostatic fluid, and it has been proved that TMP can successfully cure chronic bacterial prostatitis caused by sensitive bacteria. Long-term treatment (12 weeks) is more effective than short-term treatment (2 weeks).
In the absence of azotemia, the following antibiotics can be selected according to bacterial culture and drug sensitivity test:
SMZco (tmp160mg + smz800mg), orally, twice a day for 2 weeks;
TMP, two tablets per time (100mg / tablet), twice a day, lasting for 12 weeks;
Carboxybenzylpenicillin, 2 tablets (383mg / tablet) per time, 4 times a day, oral, for at least 4 weeks;
Dimethylaminotetracycline 100mg was taken twice a day orally for at least four weeks;
Erythromycin 500mg, oral 4 times a day for at least 4 weeks.
The principle of individual differences must be considered in special treatment, and the patient's tolerance to drugs must also be considered. Norfloxacin and ciprofloxacin are also effective drugs in the treatment of prostatitis.
Of course, other drugs are also effective in relieving symptoms:

α - receptor blocker

α - receptor blocker can relax the smooth muscle of the prostate and bladder, improve the symptoms of the lower urinary tract, and thus become the basic drug for the treatment of prostatitis. α - blockers mainly include doxazosin, naftopidil, tamsulosin, and terazosin. The course of treatment of α - blockers should be more than 12 weeks.
Plant preparations
It mainly refers to pollen preparations and plant extracts. Plant preparations include Universal Thai, Sabah palm, and its extracts, etc. The adverse reactions were minor.
M-receptor blocker

It can be used to treat prostatitis patients with overactive bladders (OAB), such as the urgency of urination, frequency of urination and nocturia, without urinary obstruction.
Antidepressants and anxiolytics
These medicines can be used to treat chronic prostatitis patients with depression and anxiety. In addition, Chinese herbal medicine Diuretic and Anti-inflammatory Pill also has a good effect on chronic bacterial prostatitis, and it is safe without side effects. It can not only eliminate the focus but also improve self immunity, so as to prevent a recurrence.
Most of the patients with chronic bacterial prostatitis can rarely be cured by medical treatment, but as long as the appropriate oral medicine is used daily to maintain a small dose of inhibitory treatment to ensure sterility in the urine (such as tmp100mg, once a day, or tmp160mg + smz800mg, once a day), the patients can be relatively adjacent. If inhibition therapy is interrupted, bladder urine will be reinfected, and symptoms will reappear.

Frequent sexual life and irregular lifestyle are the common causes of chronic bacterial prostatitis, so it is necessary to change these bad habits. Taking exercises and keeping a healthy lifestyle is also very beneficial for the treatment and rehabilitation of the disease.

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