Treatment for Chronic Pelvic Pain Syndrome

Date:2019-12-31 click:

Chronic pelvic pain syndrome(CPPS) has always been considered as the most difficult type of prostatitis to treat. It should be pointed out that the etiology of CPPS is complex, the symptoms are diverse, and a single treatment method is often difficult to achieve satisfactory results. Therefore, in recent years, combined treatment for different pathogenesis of prostatitis has achieved satisfactory results.
1. Antibiotic treatment
This treatment has been widely recognized, of which Quinolones are the most commonly used drugs. Quinolones have an affinity for the prostate, can penetrate the lipid membrane of the prostate, and reach a higher concentration in the prostate.
In addition to being effective for Gram-negative and positive bacteria, they are also effective for chlamydia and mycoplasma, so their efficacy is better. However, there are also reports suggesting that quinolones are ineffective in the treatment of CPPS. Therefore, the treatment of CPPS with antibiotics needs further multi-center Large sample clinical study.
2. α - adrenergic receptor blocker
This drug can reduce the resistance of the posterior urethra and bladder neck, reduce the urine reflux in the prostate and improve the symptoms of patients.
3. Nonsteroidal anti-inflammatory drugs(NSAIDs) and 5αreductase inhibitors
It has been confirmed that the immune system plays an important role in the pathogenesis of CPPS. The inflammation of CPPS is mediated by cytokines induced expression of chemical activator, cyclooxygenase-2 (COX-2). NSAIDs can play a dual role in anti-inflammatory and pain relief; in addition, plant drugs and 5-reductase inhibitors in the treatment of CPPS are also increasingly valued.

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