Can Chronic Nonbacterial Prostatitis Be Treated With Stem Cells?

Date:2020-08-25 click:0

In recent years, with the rapid development of stem cell technology, stem cells have prominent advantages in rapid proliferation, low immunogenicity, multidirectional differentiation, immunosuppression and tissue repair ability. 
Many studies have shown that stem cells can inhibit inflammatory response by inhibiting the proliferation of T cell, B cell and antigen-presenting cell, and the production of pro-inflammatory factors, providing a new way for effective intervention in intractable prostatitis.
Prostatitis can be classified into acute and chronic types, or bacterial and nonbacterial types. It is a male reproductive system disease with a high incidence.
The main cause of prostatitis is pathogen infection, and bacterial prostatitis accounts for 5% to 10% among patients. E.coli is the most common pathogenic bacteria, accounting for about 80%, followed by Klebsiella, Pseudomonas aeruginosa and proteus. 
The traditional intervention of bacterial prostatitis is using antibiotics. In addition, patients can choose herbal medicine Diuretic and Anti-inflammatory Pill to recuperate, which has a remarkable bactericidal effect and can effectively treat bacterial prostatitis.
For chronic nonbacterial prostatitis, the common treatment is taking medication to relieve pain and improve symptoms of abnormal urination. If it's caused by chlamydia or mycoplasma, minocycline, doxycycline and alkaline drugs are available. Besides, TCM, psychological counseling, prostate massage, biofeedback therapy, hyperthermia, transurethral prostatic perfusion and other methods can also be used.
Stem cells can treat chronic nonbacterial prostatitis as well. It has been proved that stem cells have been used in a variety of disease intervention studies due to their low immunogenicity and multidirectional differentiation. Stem cells have the limitless ability to self-replicate and differentiate into different organs and tissues of the body. 
They can also inhibit the secretion of inflammatory cytokines in macrophages, inhibit the migration of eosinophils to inflammatory sites, and produce anti-inflammatory function. It has also been shown that pure mesenchymal stem cells can effectively intervene in acute and chronic prostatitis.
The results proved that stem cell therapy effectively reduces the secretion of pro-inflammatory cytokines TNF-α and IL-1β, and reduce chronic prostatic inflammation. The researchers also found that when the stem cells are co-cultured with E.coli, the growth rate and the number of E.coli are decreased.
Due to its immunoregulatory activity and chemotaxis to damaged or inflammatory tissues, stem cell therapy has been widely used in the intervention of various inflammatory diseases with satisfactory results. It is believed that with the continuous innovation of stem cell technology, stem cell therapy will benefit all patients with chronic prostatitis.
Clinically, patients with chronic nonbacterial prostatitis are not self-healing and usually require drug treatment. At the same time, they should develop good living habits, do not sit for long, do not eat spicy foods, and keep a moderate sexual life. The prostate gland is small, but it does a great job in the body. Male patients need regular inspection to understand their physical conditions and take preventive measures.
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